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Which of the following is NOT a true statement about prostaglandins?

  1. They promote inflammation.

  2. They can constrict blood vessels only.

  3. They are produced in the renal medulla.

  4. They can lead to pain and fever.

The correct answer is: They can constrict blood vessels only.

Prostaglandins are bioactive lipids that play a crucial role in various physiological processes, including inflammation, pain modulation, and the regulation of blood flow. The statement that they can constrict blood vessels only is not accurate because prostaglandins have diverse effects on blood vessel behavior. Some types of prostaglandins can cause vasodilation, which is the widening of blood vessels, while others can indeed cause vasoconstriction, depending on the specific type of prostaglandin and the receptors they bind to. Understanding that prostaglandins can both constrict and dilate blood vessels illustrates their complex role in the body's response to injury and infection. This complexity aligns with their involvement in promoting inflammation and leading to symptoms such as pain and fever, as noted in the other statements.